Table 1

Distribution of c-Jun, N-ras, Caspase9 and p73 expression in different subtypes of thymic epithelial tumors (TETs) n (%)
Type-A Type-AB Type-B1 Type-B2 Type-B3 Tcaa MTb Total NTc Pd Pe Pf
N = 2 N = 19 N = 4 N = 14 N = 11 N = 8 N = 2 N = 60 N = 11
C-Jun 0 (0.0) 4 (21.0) 0 (0.0) 6 (42.9) 5 (45.5) 7 (87.5) 0 (0.0) 22 (36.7) 0 (0) 0.011 0.014 0.002
N-ras 1 (50.0) 3 (15.8) 0 (0.0) 1 (7.1) 5 (45.4) 2 (25.0) 0 (0.0) 12 (20.0) 3 (27.3) 0.187 0.888 0.364
Caspase9 2 (100.0) 5 (26.3) 0 (0.0) 10 (71.4) 7 (63.6) 4 (50.0) 2(100.0) 30 (50.0) 7 (63.6) 0.016 0.780 0.019
p73 1 (50.0) 5 (35.7) 0 (0.0) 9 (64.3) 8 (81.8) 4 (50.0) 1 (50.0) 28 (46.6) 1 (9.1) 0.044 0.046 0.004

Tcaa: thymic carcinoma.

MTb: metaplastic thymoma.

NTc: normal thymic tissue.

Pd: Two-sided Fisher’s exact test for distributions between different histologic subtypes of thymoma.

Pe: Two-sided Fisher’s exact test for distributions between cases and controls.

Pf: Two-sided Pearson’s chi square test for distributions between lower-grade TETs (type-A, AB, B1,MT) and higher-grade TETs (type-B2, B3, Tca).

Ma et al.

Ma et al. Diagnostic Pathology 2012 7:120   doi:10.1186/1746-1596-7-120

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