Table 2

Cox proportional hazards analysis of the prognostic interaction of SATB1 with SATB2 expression
Cancer specific survival Overall survival
HR(95%CI) p p† HR(95%CI) p p†
All SATB2 positive tumours univariable univariable
SATB1 neg 1,00 171(52) 1,00 171(67)
SATB1 pos 1.09(0.75-1.57) 0.649 192(64) 1.01(0.73-1.41) 0.932 192(77)
0.011 0.015
All SATB2 negative tumours univariable univariable
SATB1 neg 1,00 125(46) 1,00 125(56)
SATB1 pos 2.63(1.46-4.71) 0.001 22(15) 2.31(1.32-4.04) 0.003 22(16)
multivariable multivariable
SATB1 neg 1,00 115(40) 1,00 115(48)
SATB1 pos 2.07(1.06-4.05) 0.034 17(12) 2.05(1.09-3.88) 0.026 17(13)

Multivariable analysis included adjustment for age (>/<=75 years), gender, T-stage (I-II, III, IV), N-stage (0,1,2), M-stage (0, 1) and differentiation grade (high-intermediate vs low). p†: P-value for term of interaction by Cox multivariate analysis including SATB1 expression, SATB2 expression, and a term of interaction.

Nodin et al.

Nodin et al. Diagnostic Pathology 2012 7:115   doi:10.1186/1746-1596-7-115

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