Table 4 |
||||
| Correlation between grading and staging of chronic hepatitis and protein kinase R in liver tissue | ||||
| PKR gene expression in liver | ||||
|
GII (HCV-4) |
GIII (HCV-4 related HCC) |
|||
| Spearman's correlation coefficient | rs | P-value | rs | P-value |
| HAI | 0.83 | 0.0001 | 0.89 | 0.0001 |
| Fibrosis | o.56 | 0.004 | 0.84 | 0.0001 |
A significant positive correlation is obvious in which higher HAI and fibrosis scores are associated with high rate of PKR gene expression.
GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; HAI: histological activity.
Index; PKR: protein kinase R.
Mohamed et al. Diagnostic Pathology 2012 7:103 doi:10.1186/1746-1596-7-103
