Table 4

Correlation between grading and staging of chronic hepatitis and protein kinase R in liver tissue
PKR gene expression in liver

GII

(HCV-4)

GIII

(HCV-4 related HCC)

Spearman's correlation coefficient rs P-value rs P-value
HAI 0.83 0.0001 0.89 0.0001
Fibrosis o.56 0.004 0.84 0.0001

A significant positive correlation is obvious in which higher HAI and fibrosis scores are associated with high rate of PKR gene expression.

GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; HAI: histological activity.

Index; PKR: protein kinase R.

Mohamed et al.

Mohamed et al. Diagnostic Pathology 2012 7:103   doi:10.1186/1746-1596-7-103

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