Table 3

Correlation between hepatitis C virus quantitation in serum and protein Kinase R in liver tissue
Serum viral load
PKR gene expression in liver




(HCV-4 related HCC)

Spearman's correlation coefficient (rs) −0.56 −0.46
P-value 0.004 0.02

A significant negative correlation is shown between both studied groups, in which lower serum viral load was associated with higher PKR gene expression

GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; PKR: protein kinase R.

Mohamed et al.

Mohamed et al. Diagnostic Pathology 2012 7:103   doi:10.1186/1746-1596-7-103

Open Data