Figure 4.

Microscopic appearances of a bullous KS: intraepidermal bulla structure and serum exudation are observed within squamous epithelium of a nodular stage KS (A-B; H&E, A, X50, B, X100). Nuclear immunoreaction with HHV-8 ( LNA-1) is observed in a tumor tissue composed of extravasated erythrocytes and spindle cells (C; H&E, X400, D; ABC-DAB, X400).