Benign mimicking malignant, and malignant mimicking benign in the gallbladder. A-B: RAS extending transmurally, without any associated dysplasia, C: Glands embedded in bundles of smooth muscle resembling RAS, D: Well-differentiated glandular structures embedded deeply in the gallbladder wall with subtle atypia, E: Foci of back to back arrangement of glands lined by layers of highly atypical columnar cell. Many mitoses presented, F: Diffuse wall thickening with intramural diverticula within the wall, mimicking well-differentiated adenocarcinoma of the gallbladder (H&E stain).
Giang et al. Diagnostic Pathology 2012 7:10 doi:10.1186/1746-1596-7-10