Table 1

Clinical, histological, phenotypical and molecular findings in the series of 82 FL

Gender

F

46

M

36


Age

Median 58

Range 20-88


Type of FL

Nodal FL

67

Combined FL+DLBCL

10

Cutaneous

5


Pattern

"In situ neoplasia"

6 (7.8%)

Nodular

62 (80.5%)

Nodular and diffuse

5 (6.5%)

Diffuse

4 (5.2%)


WHO Grade

Grade 1

8 (11.3%)

Grade 2

37 (52.1%)

Grade 3

26 (36.6%)


Marginal differentiation

Yes

7 (9.9%)

No

64 (90.1%)


BCL6

Positive

76 (92.7%)

Negative

6 (7.3%)


CD10

Positive

74 (90.2%)

Negative

8 (9.8%)


BCL2

Positive

72 (87.8%)

Negative

10 (12.2%)


Ki67 antigen

Low

23

Intermediate

30

High

29


IGH gene rearrangement

Monoclonal

66 (80.5%)

Polyclonal

16 (19.5%)


MBR-BCL2/JH rearrangement

Present

19 (23.2%)/15 (27.3%)*

Absent

63 (76.8%)/40 (72.7%)*


* Limited to cases with successful beta-globin gene amplification.

Goteri et al. Diagnostic Pathology 2011 6:97   doi:10.1186/1746-1596-6-97

Open Data