Table 1 |
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|
Comparsion of the clinicopathologic features of malignant renal solitary fibrous tumor |
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|
Fine et al. |
Margo et al. |
Present case |
|
|
|
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|
Age (yr) |
76 |
34 |
50 |
|
|
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|
Gender |
Female |
Female |
Female |
|
|
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|
Location |
Left kidney |
Left kidney |
Right kidney |
|
|
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|
Size |
12 × 10 × 7.5 cm |
9 cm, with a distinct 3-cm nodule |
9 × 9 × 6 cm |
|
|
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|
Tumor borders |
Infiltrative with invasion beyond the renal capsule |
Circumscribed |
Circumscribed, unencapsulated |
|
|
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|
Necrosis |
Focal |
Absent |
Marked |
|
|
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|
Hemorrhage |
NA |
Absent |
Present |
|
|
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|
Histology |
10% benign SFT 90% dedifferentiation |
70% benign SFT 30% dedifferentiation |
De novo malignant SFT |
|
|
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|
Mitoses |
Frequent |
2-6/10 HPF |
8/10 HPF |
|
|
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|
Atypia |
Marked in areas of dedifferentiation |
Marked in areas of dedifferentiation |
Mild to moderate |
|
|
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|
Ki-67 proliferative index |
NA |
1-4% |
20% |
|
|
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|
CD34 |
Loss of expression in areas of dedifferentiation |
Positive |
Positive |
|
|
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|
Follow-up |
Multiple lung nodules 4 month after nephrectomy |
15 months, NED |
30 months, NED |
|
|
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|
NA: not available, NED: no evidence of disease |
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|
Hsieh et al. Diagnostic Pathology 2011 6:96 doi:10.1186/1746-1596-6-96 |
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