Table 1

Comparsion of the clinicopathologic features of malignant renal solitary fibrous tumor

Fine et al.

Margo et al.

Present case


Age (yr)

76

34

50


Gender

Female

Female

Female


Location

Left kidney

Left kidney

Right kidney


Size

12 × 10 × 7.5 cm

9 cm, with a distinct 3-cm nodule

9 × 9 × 6 cm


Tumor borders

Infiltrative with invasion beyond the renal capsule

Circumscribed

Circumscribed, unencapsulated


Necrosis

Focal

Absent

Marked


Hemorrhage

NA

Absent

Present


Histology

10% benign SFT 90% dedifferentiation

70% benign SFT 30% dedifferentiation

De novo malignant SFT


Mitoses

Frequent

2-6/10 HPF

8/10 HPF


Atypia

Marked in areas of dedifferentiation

Marked in areas of dedifferentiation

Mild to moderate


Ki-67 proliferative index

NA

1-4%

20%


CD34

Loss of expression in areas of dedifferentiation

Positive

Positive


Follow-up

Multiple lung nodules 4 month after nephrectomy

15 months, NED

30 months, NED


NA: not available, NED: no evidence of disease

Hsieh et al. Diagnostic Pathology 2011 6:96   doi:10.1186/1746-1596-6-96

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