Table 3

Concordance of HER2 immunohistochemistry maximum TMA score by visual evaluation and digital analysis

VE2max HER2 score


VE1max HER2 score

0/1+

2+

3+

Total

0/1+

129

7

0

136

2+

0

7

1

8

3+

0

1

16

17

DAmax HER2 score


VE1max HER2 score

0/1+

2+

3+

Total

0/1+

122

14

0

136

2+

0

5

3

8

3+

0

0

17

17

DAmax HER2 score


VE2max HER2 score

0/1+

2+

3+

Total

0/1+

121

8

0

129

2+

1

11

3

15

3+

0

0

17

17


The concordance per patient is based on maximum TMA spot HER2 score value: VE1max and VE2max - first and second visual evaluation by the pathologist, DAmax - digital analysis score.

Laurinaviciene et al. Diagnostic Pathology 2011 6:87   doi:10.1186/1746-1596-6-87

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