Figure 2.

Hematoxylin & Eosin (H&E) shows mild changes in glomeruli. Island-like infiltrations of medium to large atypical lymphoid cells with hyperchromatic nuclei are seen in many areas of the interstitium (A). (Magnification, ×200) Immunohistochemical staining shows the lymphoid cells to be positive for B-cell markers CD20 (B) and large B-cell lymphoma markers mum-1 (C). (Magnification, ×100) Immunohistochemical staining using anti-CD34 shows the accumulation of lymphoid cells to be localized within the peritubular capillary lumina (D). (Magnification, ×400).