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Resolution: standard / high Figure 2.
Myocardial findings in case 2. (A) Colliquative myocytolysis. Perinuclear disappearance of myofibrils with intramyocardial
edema resulting in an empty sarcolemmal tube seen in transverse sections. Note the
absence of any type of cellular reaction. (B) Contraction band necrosis: intense hypereosinophilia of the hypercontracted myocardial
cells with rhexis of the myofibrillar apparatus into cross-fiber, anomalous, and irregular
or pathological bands. The latter are formed by segments of hypercontracted sarcomeres
with scalloped sarcolemma. (C) Confocal laser microscopy: CD68 showed a strong reaction in the heart where intense
hypereosinophilia of the hypercontracted myocardial cells with rhexis of the myofibrillar
apparatus into cross-fiber, anomalous, and irregular or pathological bands is described.
(D) Confocal laser microscopy: myocyte nuclei labelled by TUNEL assay (apoptosis) revealed
an intensive, wide, positive reaction (green nuclei).
Bello et al. Diagnostic Pathology 2011 6:8 doi:10.1186/1746-1596-6-8 |