Table 4

Immunohistochemical study of Rhabdomyosarcomatous tumors and small cell carcinoma

Cases

Number of cases

Myogenin

Cytokeratin

Synaptophysin

Chromogranin

FISH in RMS


RMS*

1

Positive

Negative

Positive

Negative

negative


RMS in ca^

2

Positive in

RMS

Negative in RMS; positive in ca

Positive in RMS in 1 out of 2 cases

Negative

negative


Small cell carcinoma

13

Negative

Positive (9/9)

Positive(9/9)

Positive in 7/9

N/A


FISH DNA breakapart signal analysis for detection of translocation associated with EWS and FHKR.

*RMS: Rhabdomyosarcoma or rhabdomyosarcomatous component in appropriate setting; ^ca: Carcinoma.

Bing and Zhang Diagnostic Pathology 2011 6:66   doi:10.1186/1746-1596-6-66

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