Figure 2.

Representative examples of p16INK4A immunoreactive patterns in the normal cervical tissue and CIN. A: focal p16INK4A immunostaining in CIN1. B: diffuse p16INK4A immunostaining restricted to the lower third of the cervical epithelium in CIN1. C: diffuse p16INK4A immunostaining of more than a third of the cervical epithelium in CIN2 on the left and negative p16INK4A immunostaining in the normal cervical tissue on the right. D: diffuse p16INK4A immunostaining of full thickness of the cervical epithelium in CIN3.

Han et al. Diagnostic Pathology 2011 6:59   doi:10.1186/1746-1596-6-59
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