The histomorphological growth pattern of the liver metastasis in case 3 showed a hypercellular tumor (a) with plasmacytoid cells (b and inset) (H&E staining). Immunohistochemistry of the liver metastasis showed intensive expression of predominantly membranous C-KIT (c) and distinct membranous CD34 (d) staining. The lymph node metastases revealed closely packed hypercellular tumor nodules (e) with lymphangioinvasion (f) (H&E staining).
Otto et al. Diagnostic Pathology 2011 6:52 doi:10.1186/1746-1596-6-52