Table 1

Immunohistochemical reagents and results

Results

Antigens

Antibodies (clone)

Sources

EMEA.

CIN3


Pancytokeratin

AE1/3

Dako Corp. Glostrup, Denmark

+++

+++

Pancytokeratin

CAM5.2

Beckton-Dickinson, CA, USA

++

+

HMWCK

34βE12

Dako

+

+++

CK5/6

D5/16

Dako

+

+++

CK7

N1626

Dako

+

+

CK8

DC10

Dako

-

-

CK14

LL002

Novocastra, Newcastle upon type, UK

-

-

CK 18

DC10

Dako

+++

-

CK 19

RCK 108

Progen, Heidelberg, Germany

++

-

CK 20

K20.8

Dako

-

-

EMA

E29

Dako

-

+

Vimentin

Vim 3B4

Dako

-

-

CEA

polyclonal

Dako

-

-

CA19-9

NS19-9

TBF Lab, Tokyo Japan

+

+

CA125

NS125

TFB Lab

+++

+

Desmin

D33

Dako

-

-

ASMA

1A4

Dako

-

-

p53 protein

DO-7

Dako

+

+

p63

4A4

Dako

-

+++

Chromogranin

DAK-A3

Dako

-

-

Synaptophysin

Polyconal

Dako

-

-

CD56

UJ13A

Dako

-

-

CD68

KP-1

Dako

-

-

ER

M7047

Dako

+++

+++

PgR

1A6

Novocastra

+++

-

HER2/neu

CB11

Ventana Japan, Tokyo

-

-

MUC1

Ma695

Novocastra

-

+

MUC2

CCp58

Novocastra

-

-

MUC5AC

CLH2

Novocastra

-

-

MUC6

CLH5

Novocastra

-

-


+++, strongly positive. ++, moderately positive. +, mildly positive. -, negative. EMEA, early microinvasive endometrioid adenocarcinoma. CIN3, cervical intraepithelial neoplasm grade 3. HMWCK, high molecular weight cytokeratin. CK, cytokeratin. EMA, epithelial membrane antigen. CEA, carcinoembryonic antigen. CA19-9, carbohydrate antigen 19-9. CA125, carbohydrate antigen 125. ASMA, α-smooth muscle antigen. ER, estrogen receptor. PgR, progesterone receptor.

Terada Diagnostic Pathology 2011 6:51   doi:10.1186/1746-1596-6-51

Open Data