Receiver operating characteristic (ROC) curves for the 6 genes in NSCLC. All tumor and nonmalignant lung tissues for which there was complete DNA methylation data were used for the analyses. The ROC curves plot sensitivity vs. 100-specificity. The determined cut-off values for CALCA, CDH1, DAPK1, IRX2, TIMP3, and PAX6 were 45.7, 29.0, 0, 58.8, 48.2, and 13.0, respectively.
Ji et al. Diagnostic Pathology 2011 6:48 doi:10.1186/1746-1596-6-48