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Lymphoepithelioma-like carcinoma of the vulva, an underrecognized entity? Case report with a single inguinal micrometastasis detected by sentinel node technique

Hans Bösmüller1*, Sophie Haitchi-Petnehazy1, Christine Gruber1, Franz Roithmeier2, Wolfgang Stummvoll2 and Gerald Webersinke3

Author affiliations

1 Dept. of Pathology, Krankenhaus Barmherzige Schwestern, Linz, Austria

2 Dept. of Gynecology, Krankenhaus Barmherzige Schwestern, Linz, Austria

3 Laboratory of Molecular Biology and Tumorcytogenetics, I. Internal dept., Krankenhaus Barmherzige Schwestern, Linz, Austria

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Citation and License

Diagnostic Pathology 2011, 6:4  doi:10.1186/1746-1596-6-4

Published: 10 January 2011


This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy. Follow-up nine months later showed only slight vulvar atrophy, without signs of local recurrence or distant metastases.

Although lymphoepithelioma-like carcinomas of the skin and the female genital tract are presumed to have a better prognosis than their counterparts in the upper aerodigestive tract, possibly due to earlier detection and therapy, this case documents their potential for early metastasis.