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Open Access Case Report

Malignant mesenchymal tumor with leiomyosarcoma, rhabdomyosarcoma, chondrosarcoma, and osteosarcoma differentiation: case report and literature review

Yao-Feng Li1, Cheng-Ping Yu14, Seng-Tang Wu2, Ming-Shen Dai3 and Herng-Sheng Lee14*

Author Affiliations

1 Department of Pathology, Tri-Service General Hospital, Taipei, Taiwan, China

2 Division of Urology, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan, China

3 Division of Oncology, Department of Internal medicine, Tri-Service General Hospital, Taipei, Taiwan, China

4 National Defense Medical Center, Taipei, Taiwan, China

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Diagnostic Pathology 2011, 6:35  doi:10.1186/1746-1596-6-35

Published: 15 April 2011

Abstract

A case of malignant mesenchymoma of the bladder containing leiomyosarcoma, rhabdomyosarcoma, chondrosarcoma, osteosarcoma, and myxomatous components is described. The primary pedunculated tumor measuring 14 × 13 × 7 cm and weighing 343 g arose from the left trigone of the bladder and was treated by total cystectomy. The histogenesis of malignant mesenchymomas and their optimal management strategy and prognosis remain uncertain. Herein, we present the fifth case of malignant mesenchymoma of the urinary bladder to be reported in the literature, which presented five unrelated differentiated tissues more than did previously reported cases.

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