Table 1

Gelatinolytic score calculated for biopsy prints of PCa and BPH biopsies

Gleason Score

PSA (ng/ml)

Biopsy MMP9+MMP2 score (BS)

Gelatinolytic score (GS)

Correlation


PCa

9

7.0

5+2

4

BS vs GS = 0.97 * Gleason vs GS = 0.86 *

PSA (PCa) vs GS = 0.02

PSA (all) vs GS = 0.36

PCa

8

6.0

5+1

4

PCa

8

14.2

3+2

3

PCa

7

8.3

3+0

2

PCa

6

26.0

3+1

2

PCa

6

8.2

2+0

0

PCa

6

14.8

3+1

2

PCa

6

5.9

0

0

PCa

6

10.5

1+1

1

BPH

--

3.0

0

0

BPH

--

0.4

0

0

BPH

--

3.2

0

0


In the corresponding needle biopsies MMP2 and MMP9 expressions were evaluated by immunohistochemistry and a semiquantitative score (BS) was calculated. Correlation coefficients between BS and GS, between GS and Gleason score and between GS and PSA are shown. The correlation coefficient was calculated for all PSA values or only for PSA values from PCa patients (* p< 0.01)

Angelucci et al. Diagnostic Pathology 2011 6:34   doi:10.1186/1746-1596-6-34

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