Table 1 |
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|
Peak statistics - comparison of statistically important (p value of T-test/ANOVA < 0.05) peaks for data separation and recognition capability (biomarkers candidates). |
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|
Mass (Da) |
Mean (Control) |
Mean (Pathological) |
P value T-Test/ANOVA |
P value Wilcoxon/Kruskal-Wallis |
Difference Average |
|
|
|||||
|
8616.14 |
0.32 |
1.45 |
< 0.000001 |
0.00000847 |
< 0.000001 |
|
|
|||||
|
6228.05 |
1.55 |
4.07 |
< 0.000001 |
0.00152 |
< 0.000001 |
|
|
|||||
|
5759.35 |
1.54 |
2.65 |
< 0.000001 |
0.00017 |
0.000773 |
|
|
|||||
|
3588.09 |
1.99 |
4.82 |
< 0.000001 |
0.00017 |
< 0.000001 |
|
|
|||||
|
7596.85 |
0.81 |
2.11 |
< 0.000001 |
0.00154 |
< 0.000001 |
|
|
|||||
|
5201.26 |
1.93 |
3.87 |
< 0.000001 |
0.000366 |
< 0.000001 |
|
|
|||||
|
4156.39 |
2.08 |
4.87 |
< 0.000001 |
0.00017 |
0.0000021 |
|
|
|||||
|
9554.61 |
0.78 |
1.99 |
0.00000228 |
0.11 |
< 0.000001 |
|
|
|||||
|
12350.75 |
0.25 |
1.22 |
0.00000228 |
0.0000289 |
< 0.000001 |
|
|
|||||
|
3603.83 |
2.11 |
4.11 |
0.0000024 |
0.0162 |
< 0.000001 |
|
|
|||||
|
6723.40 |
20.93 |
8.96 |
0.00000228 |
0.00000855 |
0.000101 |
|
|
|||||
|
11297.49 |
0.45 |
0.97 |
0.00000228 |
0.00807 |
< 0.000001 |
|
|
|||||
|
10268.09 |
0.59 |
1.56 |
0.00000341 |
0.000314 |
< 0.000001 |
|
|
|||||
|
10525.25 |
0.3 |
1.19 |
0.00000695 |
0.00017 |
< 0.000001 |
|
|
|||||
|
5800.39 |
1.79 |
3.82 |
0.00000122 |
0.195 |
< 0.000001 |
|
|
|||||
|
5910.05 |
1.78 |
3.59 |
0.00000596 |
0.00375 |
< 0.000001 |
|
|
|||||
|
10403.69 |
0.47 |
1.43 |
0.000225 |
0.000331 |
< 0.000001 |
|
|
|||||
|
8297.66 |
0.95 |
1.62 |
0.000225 |
0.176 |
< 0.000001 |
|
|
|||||
|
4570.52 |
4.96 |
7.49 |
0.000296 |
0.106 |
< 0.000001 |
|
|
|||||
|
9440.24 |
0.71 |
1.08 |
0.000296 |
0.11 |
< 0.000001 |
|
|
|||||
|
6656.68 |
6.27 |
2.07 |
0.000608 |
0.00000986 |
< 0.000001 |
|
|
|||||
|
11325.26 |
0.67 |
1.09 |
0.00168 |
0.488 |
< 0.000001 |
|
|
|||||
|
9172.09 |
34.55 |
12.13 |
0.00171 |
0.00017 |
< 0.000001 |
|
|
|||||
|
7042.18 |
23.45 |
5.42 |
0.00252 |
0.0000902 |
< 0.000001 |
|
|
|||||
|
6020.90 |
5.33 |
2.28 |
0.00252 |
0.00017 |
< 0.000001 |
|
|
|||||
|
11185.69 |
0.75 |
1.19 |
0.00252 |
0.891 |
< 0.000001 |
|
|
|||||
|
4995.04 |
2.28 |
3.87 |
0.00409 |
0.162 |
< 0.000001 |
|
|
|||||
|
8456.35 |
1.25 |
2.82 |
0.00517 |
0.31 |
< 0.000001 |
|
|
|||||
|
9960.78 |
0.78 |
1.82 |
0.0059 |
0.211 |
< 0.000001 |
|
|
|||||
|
7283.97 |
39.59 |
7.2 |
0.00715 |
0.000151 |
< 0.000001 |
|
|
|||||
|
7249.02 |
2.69 |
1.77 |
0.00757 |
0.0042 |
0.00064 |
|
|
|||||
|
7173.62 |
4.21 |
7.46 |
0.00935 |
0.647 |
< 0.000001 |
|
|
|||||
|
5711.21 |
4.23 |
6.21 |
0.00935 |
0.441 |
< 0.000001 |
|
|
|||||
|
9378.33 |
1.82 |
1 |
0.00935 |
0.00238 |
< 0.000001 |
|
|
|||||
|
4048.24 |
4.11 |
7.16 |
0.0141 |
0.176 |
< 0.000001 |
|
|
|||||
|
5837.80 |
2.19 |
3.04 |
0.0197 |
0.423 |
< 0.000001 |
|
|
|||||
|
3907.34 |
41.93 |
14.71 |
0.021 |
0.00771 |
< 0.000001 |
|
|
|||||
|
10840.50 |
0.99 |
2.24 |
0.0231 |
0.149 |
0 |
|
|
|||||
|
6745.30 |
2.08 |
1.56 |
0.0392 |
0.0221 |
0.00817 |
|
|
|||||
|
Waloszczyk et al. Diagnostic Pathology 2011 6:22 doi:10.1186/1746-1596-6-22 |
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