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Open Access Open Badges Case Report

High grade angiosarcoma arising in fibroadenoma

Emina Babarović1*, Gordana Zamolo1, Elvira Mustać1 and Miroslav Strčić2

Author Affiliations

1 Department of Pathology, School of Medicine, University of Rijeka, Braće Branchetta 20, Rijeka, Croatia

2 Department of General Surgery, Rijeka University Hospital Center, Krešimirova 42, Rijeka, Croatia

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Diagnostic Pathology 2011, 6:125  doi:10.1186/1746-1596-6-125

Published: 20 December 2011


Primary angiosarcoma of the breast is a rare tumour that account for fewer than 0.05% of all malignant mammary tumours. Angiosarcoma may have an perfidious clinical onset. Radiologic findings are often nonspecific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the high rates of local recurrence and early development of metastases. Aggressive surgical resection is the mainstay of treatment. The role of adjuvant therapy has not yet been well established.

Here we present a case of a 53 year old, postmenopausal women with primary angiosarcoma arising in fibroadenoma. To our knowledge, this is the first case described in the literature to date.

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Breast; fibroadenoma; primary angiosarcoma; mastectomy