High grade angiosarcoma arising in fibroadenoma
1 Department of Pathology, School of Medicine, University of Rijeka, Braće Branchetta 20, Rijeka, Croatia
2 Department of General Surgery, Rijeka University Hospital Center, Krešimirova 42, Rijeka, Croatia
Diagnostic Pathology 2011, 6:125 doi:10.1186/1746-1596-6-125Published: 20 December 2011
Primary angiosarcoma of the breast is a rare tumour that account for fewer than 0.05% of all malignant mammary tumours. Angiosarcoma may have an perfidious clinical onset. Radiologic findings are often nonspecific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the high rates of local recurrence and early development of metastases. Aggressive surgical resection is the mainstay of treatment. The role of adjuvant therapy has not yet been well established.
Here we present a case of a 53 year old, postmenopausal women with primary angiosarcoma arising in fibroadenoma. To our knowledge, this is the first case described in the literature to date.
The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1812981492621981 webcite.