Table 2 |
|||
|
Comparison between 2 groups of HCC patients: positive and negative SCCA immunostaining |
|||
|
Variable |
Positive SCAA |
Negative SCCA |
p value |
|
|
|||
|
Age (years) |
63.3 ± 10.8 |
62.4 ± 9.84 |
NS |
|
HBV infection (positive, %) |
27.45 |
30.00 |
NS |
|
HCV infection (positive, %) |
50.98 |
40.00 |
NS |
|
Alcohol (positive, %) |
5.88 |
10.00 |
NS |
|
Other CLD (positive, %) |
74.51 |
80.00 |
NS |
|
Serum AFP level (ng/mL) |
4853.41 ± 11432.3 |
736.24 ± 1072.51 |
0.027 |
|
Mean tumor size (cm) |
5.13 ± 4.09 |
6.12 ± 2.71 |
NS |
|
Tumor number (> 1, %) |
84.62 |
87.88 |
NS |
|
Tumor differentiation (%) |
0.022 |
||
|
Well |
37.25 |
30 |
|
|
Moderate |
52.94 |
20 |
|
|
Poor |
3.92 |
30 |
|
|
TUNEL score |
0.24 ± 0.25 |
0.41 ± 0.30 |
0.08 |
|
Ki67 score |
0.10 ± 0.11 |
0.319 ± 0.22 |
> 0.0001 |
|
AFP immunostaining (negative, %) |
60.0 |
70.7 |
NS |
|
Liver transplantation (%) |
31.37 |
10.0 |
NS |
|
Hepatic resection (%) |
60.0 |
54.9 |
NS |
|
Chemoembolization (%) |
60.0 |
52.94 |
NS |
|
Survival (months) |
39.78 ± 34.78 |
19.13 ± 20.88 |
0.026 |
|
|
|||
|
Abbreviations: HBV = hepatitis B virus; HCV = hepatitis C virus; CLD = chronic liver disease; AFP = alpha feto protein; TUNEL = Terminal Deoxynucleotidyl Transferase dUTP Nick End Labeling |
|||
|
Schmilovitz-Weiss et al. Diagnostic Pathology 2011 6:121 doi:10.1186/1746-1596-6-121 |
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