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Open Access Highly Accessed Case Report

Epithelioid hemangioendothelioma of the forearm with radius involvement. Case report

Claudia D Gherman1 and Daniela Fodor2*

Author Affiliations

1 Surgical Clinic No. 2, "Iuliu Hatieganu" University of Medicine and Pharmacy, No. 4-6 Clinicilor Street, 400006 Cluj-Napoca, Romania

2 Medical Clinic No. 2, "Iuliu Hatieganu" University of Medicine and Pharmacy, No. 4-6 Clinicilor Street, 400006 Cluj-Napoca, Romania

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Diagnostic Pathology 2011, 6:120  doi:10.1186/1746-1596-6-120

Published: 6 December 2011

Abstract

Epithelioid hemangioendothelioma (EHE) is a rare, well-differentiated endothelial tumor with intermediate malignancy which develops more frequently from the peripheral veins, generally in the lower limb. Bone EHE comprises less than 1% of the bone neoplasms. We present the case of a young man, 24-year-old, with EHE of the forearm with secondary involvement of the distal radius. The location and the extension of the tumor allowed a wide excision, without the reconstruction of radius, followed by adjuvant radiotherapy, with a subsequent favorable evolution. Based on the clinical, radiographic, and pathological features of the EHE review, we concluded that it is difficult to adopt a standardized therapeutic approach due to the extremely low incidence of the bone involvement in EHE and the variable tendencies towards malignancy of this tumor. To our knowledge this is the third case of EHE with the involvement of the radius.

Keywords:
vascular tumor; intermediate-malignant tumor; secondary bone involvement