Photomicrographs showing immunohistochemistry for neuronal markers. (a) neuron-specific enolase (NSE), (b) microtubule-associated protein-2 (MAP-2), (c) Synaptophysin, (d) neuronal nuclear antigen (NeuN), (e) tubulin, βIII isoform (TuJ1). The markers in a-d were diffusely positive in the part of the tumor with neuronal differentiation. However, TuJ1 was only weakly positive there. Olig2-positive cells were also observed in the same area (f). The cells comprising the perivascular pseudorosette were strongly positive for NSE (g) and MAP-2 (h), a-f: ×100; g and h: ×200.
Yano et al. Diagnostic Pathology 2011 6:119 doi:10.1186/1746-1596-6-119