Table 1

Frequencies of methylation of analyzed genes in PB and breast tumors.

GENE

Chromosomal region targeted by assay *

Number of paired samples used/excluded**

Methylated in both blood and tumor

Sample no. (%)

Methylated only tumor***

Methylated only PBL

Sample no. (%)


BRCA1

chr17:41, 277, 382-41, 277, 409

75/6

3 (4.3%)

23%

3 (4.3%)


APC

chr5:112, 073, 470-112, 073, 516

75/3

3 (4.1%)

83%

2 (2.7%)


RASSF1A

chr3:50, 377, 755-50, 378, 089

75/2

0%

97%

0


* UCSC Genome Browser on Human Feb. 2009 (GRCh37/hg19) Assembly

** Samples excluded due to failure of PCR amplification

*** Out of all tumor samples used

Wojdacz et al. Diagnostic Pathology 2011 6:116   doi:10.1186/1746-1596-6-116

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