Table 2 |
||||
|
Correlation of nuclear beta-catenin expression in SLN(s) with clinicopathological characteristics |
||||
|
Characteristics |
Nuclear beta-catenin expression |
P* |
||
|
|
||||
|
n |
≤ 50% |
> 50% |
||
|
|
||||
|
Gender |
||||
|
Male |
247 |
178 |
69 |
0.745 |
|
Female |
108 |
76 |
32 |
|
|
Age |
||||
|
≤ 55 |
54 |
15 |
39 |
< 0.001 |
|
> 55 |
301 |
239 |
62 |
|
|
Tumour localization |
||||
|
Rectum |
203 |
145 |
58 |
0.954 |
|
Colon |
152 |
109 |
43 |
|
|
Tumour size (cm) |
||||
|
≤ 5 |
120 |
90 |
30 |
0.303 |
|
≤ 5 |
235 |
164 |
71 |
|
|
Type of tumour |
||||
|
Adenocarcinoma |
299 |
221 |
78 |
< 0.001 |
|
Mucinous adenocarcinoma |
31 |
11 |
20 |
|
|
Signet-ring cell carcinoma |
16 |
14 |
2 |
|
|
Undifferentiated carcinoma |
9 |
8 |
1 |
|
|
Tumour cell differentiation |
||||
|
Well/moderately differentiated |
279 |
218 |
61 |
< 0.001 |
|
Poorly differentiated |
76 |
36 |
40 |
|
|
Tumour invasion depth |
||||
|
T1 |
5 |
5 |
0 |
< 0.001 |
|
T2 |
63 |
56 |
7 |
|
|
T3 |
252 |
176 |
76 |
|
|
T4 |
35 |
17 |
18 |
|
|
Lymph node metastasis |
||||
|
< 4 |
123 |
100 |
23 |
0.003 |
|
≥ 4 |
232 |
154 |
78 |
|
|
Liver metastasis |
||||
|
Negative |
262 |
231 |
31 |
< 0.001 |
|
Positive |
93 |
23 |
70 |
|
|
TNM stage |
||||
|
I |
5 |
5 |
0 |
< 0.001 |
|
II |
20 |
20 |
0 |
|
|
III |
237 |
206 |
31 |
|
|
IV |
93 |
23 |
70 |
|
|
|
||||
|
* P value is the result of χ2 test in the same factor, and < 0.05 is considered statistically significant. |
||||
|
Cheng et al. Diagnostic Pathology 2011 6:109 doi:10.1186/1746-1596-6-109 |
||||
