Table 2

Correlation between FISH EGFR and immunohistochemicals markers (mEGFR, nEGFR and Cyclin D1)

EGFR FISH


Parameters

Total

≤ 2,0 - 2,49

2,5 - 2,93

≥ 2,94

p - value


mEGFR

0.001

neg./week

49

49

0

0

moderate

64

53

8

3

strong

22

15

2

5

nEGFR

0.818

neg./week

9

9

0

0

moderate

49

42

2

5

strong

77

66

8

3

Cyclin D1

0.876

neg./week

8

7

1

0

moderate

51

45

1

5

strong

76

65

8

3


Total

135

117


CRC, colorectal carcinoma

mEGFR, membrane EGFR

nEGFR, nuclear EGFR

test - Spearman rank correlation coefficient

Dekanić et al. Diagnostic Pathology 2011 6:108   doi:10.1186/1746-1596-6-108

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