Table 2 |
|||||
|
Correlation between FISH EGFR and immunohistochemicals markers (mEGFR, nEGFR and Cyclin D1) |
|||||
|
EGFR FISH |
|||||
|
|
|||||
|
Parameters |
Total |
≤ 2,0 - 2,49 |
2,5 - 2,93 |
≥ 2,94 |
p - value |
|
|
|||||
|
mEGFR |
0.001 |
||||
|
neg./week |
49 |
49 |
0 |
0 |
|
|
moderate |
64 |
53 |
8 |
3 |
|
|
strong |
22 |
15 |
2 |
5 |
|
|
nEGFR |
0.818 |
||||
|
neg./week |
9 |
9 |
0 |
0 |
|
|
moderate |
49 |
42 |
2 |
5 |
|
|
strong |
77 |
66 |
8 |
3 |
|
|
Cyclin D1 |
0.876 |
||||
|
neg./week |
8 |
7 |
1 |
0 |
|
|
moderate |
51 |
45 |
1 |
5 |
|
|
strong |
76 |
65 |
8 |
3 |
|
|
|
|||||
|
Total |
135 |
117 |
|||
|
|
|||||
|
CRC, colorectal carcinoma mEGFR, membrane EGFR nEGFR, nuclear EGFR test - Spearman rank correlation coefficient |
|||||
|
Dekanić et al. Diagnostic Pathology 2011 6:108 doi:10.1186/1746-1596-6-108 |
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