Western Blot analysis of SELENBP1 expression in uterine leiomyoma and normal myometrium. (A) The bands of SELENBP1 in two examples displayed about 4-fold lower density in leiomyoma than in normal myometrium. (B) After normalizing for β-actin and then for the mean of SELENBP1 in normal myometrium, data derived from densitometry of Western Blot experiments were used to represent relative levels of SELENBP1. Wilcoxon Signed-Ranked test for Matched Pairs showed a significant decrease of SELENBP1 level in leiomyoma compared to that in normal myometrium. The vertical bars in B represent means and standard deviations. Abbreviations: LM, leiomyoma; MM, normal myometrium; SELENBP1, selenium-binding protein1 1; n, number of cases.
Zhang et al. Diagnostic Pathology 2010 5:80 doi:10.1186/1746-1596-5-80