Table 1 |
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Clinicopathologic factors of 34 patients with metaplastic breast carcinoma |
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|
Age (years), mean (range) |
61.8 (32-90) |
|
|
|
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|
Histologic grade, n (%) |
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|
Low grade |
6 (17.6%) |
|
|
Intermediate grade |
2 (5.9%) |
|
|
High grade |
26 (76.5%) |
|
|
|
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|
Histologic subtypes |
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|
Spindle cell |
20 (58.8%) |
|
|
Mixed squamous and spindle cell |
5 (14.7%) |
|
|
Squamous |
4 (11.8%) |
|
|
Matrix producing |
3 (8.8%) |
|
|
Adenosquamous |
2 (5.9%) |
|
|
|
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|
Tumor diameter (cm), median (range) |
3.0 (0.8-24) |
|
|
|
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|
Tumor size |
T1 |
10 (29.4%) |
|
T2 |
14 (41.2%) |
|
|
T3 |
6 (17.6%) |
|
|
T4 |
4 (11.8%) |
|
|
|
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|
Receptor Status |
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|
ER positive |
4 (12.1%) |
|
|
PR positive |
3 (9.1%) |
|
|
Her2 positive |
2 (5.9%) |
|
|
|
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|
Lymph node status |
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|
Positive |
5 (14.7%) |
|
|
Negative |
29 (85.3%) |
|
|
|
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|
Surgery |
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|
Mastectomy |
21 (61.8%) |
|
|
BCT |
13 (38.2%) |
|
|
|
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|
Adjuvant treatment |
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|
Chemotherapy |
14 (41.2%) |
|
|
Radiation |
17 (50.0%) |
|
|
|
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|
Recurrence |
Local |
3 (8.8%) |
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Distant |
4 (11.8%) |
|
|
|
||
|
Overall survival, median (95% CI*) |
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|
1 year |
82.8% (70.1%, 97.8%) |
|
|
3 years |
58.4% (42.0%, 81.4%) |
|
|
|
||
|
Disease-free survival, median (95% CI*) |
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|
1 year |
78.5% (64.4%, 95.5%) |
|
|
3 years |
71.3% (54.4%, 93.6%) |
|
|
|
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|
*CI = Confidence Interval |
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|
Nassar et al. Diagnostic Pathology 2010 5:76 doi:10.1186/1746-1596-5-76 |
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