Table 2 |
||||||||
|
Summary of biomarker expression for the second whole tissue section quantification |
||||||||
|
Distribution of expression values |
||||||||
|
Biomarker |
Quantitation Method* |
0% (min) |
10% |
25% |
50% (median) |
75% |
90% |
100% (max) |
|
|
||||||||
|
B7-H1 |
% |
0 |
0 |
0 |
0 |
0 |
0 |
10 |
|
B7-H3 |
% |
0 |
0 |
0 |
0 |
0 |
5 |
100 |
|
IMP3 |
% |
0 |
0 |
0 |
0 |
0 |
10 |
80 |
|
CAIX |
% |
0 |
20 |
100 |
100 |
100 |
100 |
100 |
|
Survivin |
mm2 |
0.65 |
1.95 |
2.61 |
4.56 |
12.38 |
25.41 |
82.08 |
|
Ki-67 |
mm2 |
0.65 |
2.61 |
12.05 |
24.76 |
41.69 |
68.08 |
329.64 |
|
|
||||||||
|
*The membranous and cytoplasmic staining patterns of B7-H1, B7-H3, IMP3, and CAIX were quantitated as the percentage of positive tumor cells in 5-10% increments, whereas the nuclear staining patterns of survivin and KI-67 were quantitated as the number of positive tumor cells per mm2. |
||||||||
|
Eckel-Passow et al. Diagnostic Pathology 2010 5:48 doi:10.1186/1746-1596-5-48 |
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