Table 7

Histological grading of atypia and immune reaction for main MM markers

Grade of atypia

(n = 49)

Cases

(n)

Percent

(%)

Calretinin, nucleus

(n = 49)

Epithelial membrane antigen,

cell membrane

(n = 49)

Podoplanin

(n = 47)

Mesothelin

(n = 48)

Ber-Ep4

(n = 49)

1

0

0

-

-

-

-

-

1.5

2

4

4

4

1

3

4

3

4

4

0

0

2

25

51

2.84

(1...4)

2.00

(0...4)

2.65

(1...4)

3.46

(0...4)

.08

(0...1)

2.5

19

39

2.26

(near 0...4)

2.16

(near 0...4)

1.74

(0...4)

3.11

(0...4)

.11

(0...1)

3

3

6

2

3

1; 1

2

2

2; 1

1

1

1

2

1

1

0

0

0

Number of MM cells with positive IR, semiquantitatively on a 0...4 scale (steps of 25%). For grades 2 and 2.5, average values and overall minimum-maximum ranges are indicated. IR for CEA was negative in all of the cases.

Sandeck et al. Diagnostic Pathology 2010 5:47   doi:10.1186/1746-1596-5-47