Table 1

Clinicopathological Summary of Patients with Gallbladder Carcinoma and HCG

No

Age/sex

Cholelithiasis

Macroscopic type

Microscopic type

Immunostains

s/u HCG

Ref. No

1

63/F

+

Non-specific

AC + Choriocarcinoma

HCG (-)

ND

1

2

29/F

+

Protruded

AC + Choriocarcinoma

HCG (+), AFP (-), CEA (-)

Elevated

2

3

48/F

-

Protruded

AC + Choriocarcinoma

HCG (+)

Elevated

3

4

83/F

-

Protruded

ASC

HCG (+), AFP(-), CEA (+)

Elevated

4

5

68/F

-

Infiltrating

UC, pleomorphic type

HCG (+), VIM (+), CEA (+)

ND

5

6

65/F

+

Protruded

UC, pleomorphic type

HCG (+), Som (+), CEA (+)

ND

5

7

68/F

+

Protruded

UC, pleomorphic type

HCG (+), PP (+), Som (+), Gas (+), CEA (+)

ND

5

8

68/F

-

Infiltrating

UC, pleomorphic type

HCG (+), Gas (+), CEA (+)

ND

5

9

69/M

-

Protruded

UC, spindle cell or ps

HCG (+), Vim (+), Gas (+), CEA (+)

ND

5

10

61/M

-

Protruded

UC, spindle cell or ps

HCG (+), Vim (+), Som (+), Gas (+), CEA (+)

ND

5

11

66/M

-

Protruded

UC, spindle cell or ps

HCG (+), Vim (+), PP (+), CEA (+)

ND

5

12

61/F

+

Protruded

UC, spindle cell or ps

HCG (+), Vim (+), PP (+), Ser(+), Som (+), Gas (+), CEA (+)

ND

5

13

62/F

+

Infiltrating

UC, spindle cell or ps

HCG (+), Vim(+), Ser(+), Som(+), Gas (+), CEA (+)

ND

5

14

41/F

ND

ND

ETT

HCG (+), PlAP (+)

Elevated

6

15

79/M

-

Protruded

AC

HCG (+), PlAP (+)

NM

*

s/u:serum and/or urinary; HCG:human chorionic gonadotropin; AC:adenocarcinoma; ND:not described; AFP:alfa-fetoprotein; CEA:carcinoembryonic antigen; ASC:adenosquamous cell carcinoma; UC:undifferentiated carcinoma; Vim:vimentin; Som:somatostatin; PP:pancreatic polypeptide; Gas:gastrin; ps:pseudosarcomatous; Ser:serotonin; ETT: extrauterine trophoblastic tumor; PlAP:placental alkaline phosphatase; NM:not measured; *:our case.

Sato et al. Diagnostic Pathology 2010 5:46   doi:10.1186/1746-1596-5-46