Primary follicular lymphoma of the fallopian tube found incidentally in a patient treated for endometrial carcinoma: a case report
1 Department of Pathology and Laboratory Medicine, Rhode Island Hospital, APC 12 593 Eddy Street, Providence RI 02903 USA
2 Department of Pathology and Laboratory Medicine, Women and Infants Hospital, 101 Dudley Street, Providence RI 02905 USA
Diagnostic Pathology 2010, 5:44 doi:10.1186/1746-1596-5-44Published: 28 June 2010
We report a rare case of primary lymphoma of fallopian tube in a 68-year-old woman who underwent total hysterectomy and bilateral salpingo-oophorectomy for endometrial carcinoma. The specimen showed a well-differentiated endometrioid adenocarcinoma with superficial myometrial invasion. The left fallopian tube revealed a 1 cm nodule that histologically showed diffuse lymphoid follicles consisting of small cleaved lymphocytes and occasional larger cells. The cells were immunopositive for CD20, BCL-2, and BCL-6 but negative for CD3 and CD43. Polymerase chain reaction confirmed a monoclonal B-cell population. Fluorescence in-situ hybridization revealed at (14, 18) translocation. The patient had absent lymphadenopathy and negative CT scan of chest, abdomen, and pelvis. The findings were consistent with a primary low grade follicular lymphoma of fallopian tube. She did not receive chemotherapy and remained disease free for 13 months after surgery. Our case suggests that primary lymphoma of fallopian tube may be associated with a favorable prognosis.