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Pancreatic intraductal papillary mucinous neoplasm with concomitant heterotopic pancreatic cystic neoplasia of the stomach: a case report and review of the literature

Dimitrios Tsapralis13, Alexandros Charalabopoulos13, Eva Karamitopoulou23, Dimitrios Schizas13, Konstantinos Charalabopoulos23*, Theodoros Liakakos13 and Anastasios Macheras13

Author Affiliations

1 Third Department of Surgery, Athens University Medical School, Attikon University Hospital, Athens, Greece

2 Department of Pathology, Athens University Medical School, Attikon University Hospital, Athens, Greece

3 Department of Physiology, Clinical Unit, Ioannina University Medical School, Ioannina, Greece

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Diagnostic Pathology 2010, 5:4  doi:10.1186/1746-1596-5-4

Published: 14 January 2010


A 60-year-old Caucasian male underwent a total pancreatectomy for a mixed type pancreatic intraductal papillary mucinous neoplasm (IPMN) arising in the main and secondary pancreatic ducts. During surgery, a subserosal polypoid mass was noted at the greater curvature of the gastric antrum and was enucleated. This mass was proven to be heterotopic pancreatic tissue with cystic neoplasia of the IPMN histologic subtype. Through an extensive search of the literature, we found that this is the first case ever reported with simultaneous existence of IPMN changes, in the main and secondary ducts of the orthotopic pancreas and in the heterotopic pancreatic tissue of the gastric wall.