Table 2

Association of PTEN and VEGF expression and pathological features of laryngeal carcinoma (mean ± standard error of mean).

PTEN

VEGF



N(%)

Negative

26

Mild

43

Severe

71

p

Negative

10

Mild

28

Severe

102

p


MVD

140

51.9 ± 5.9

46.7 ± 3.6

41.3 ± 2.3

0.120

32.0 ± 6.3

44.4 ± 4.4

46.4 ± 2.3

0.175

Tumor size (mm)

3.1 ± 0.2

2.8 ± 0.2

3.2 ± 0.1

0.311

1.9 ± 0.2

3.1 ± 0.2

3.1 ± 0.1

0.0006

Lymph node

0.024

0.048*

No

91

18(20)

34(37)

39(43)

10(11)

20(22)

61(67)

Yes

49

7(14)

9(19)

33(67)

0

8(16)

41(84)

Cartilage invasion

0.128

0.129*

No

69

15(22)

25(36)

29(42)

10(14)

13(19)

46(67)

Yes

71

11(16)

18(25)

42(59)

0

15(21)

56(79)


*: Mild and negative cells were combined in VEGF line because of less than 5 in some cells (Fisher's exact test). MVD, microvessel density; PTEN, phosphatase and tensin homolog deleted in chromosome ten; VEGF, vascular endothelial growth factor.

Sullu et al. Diagnostic Pathology 2010 5:35   doi:10.1186/1746-1596-5-35

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