Table 2 |
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|
Association of PTEN and VEGF expression and pathological features of laryngeal carcinoma (mean ± standard error of mean). |
|||||||||
|
PTEN |
VEGF |
||||||||
|
|
|
||||||||
|
N(%) |
Negative 26 |
Mild 43 |
Severe 71 |
p |
Negative 10 |
Mild 28 |
Severe 102 |
p |
|
|
|
|||||||||
|
MVD |
140 |
51.9 ± 5.9 |
46.7 ± 3.6 |
41.3 ± 2.3 |
0.120 |
32.0 ± 6.3 |
44.4 ± 4.4 |
46.4 ± 2.3 |
0.175 |
|
Tumor size (mm) |
3.1 ± 0.2 |
2.8 ± 0.2 |
3.2 ± 0.1 |
0.311 |
1.9 ± 0.2 |
3.1 ± 0.2 |
3.1 ± 0.1 |
0.0006 |
|
|
Lymph node |
0.024 |
0.048* |
|||||||
|
No |
91 |
18(20) |
34(37) |
39(43) |
10(11) |
20(22) |
61(67) |
||
|
Yes |
49 |
7(14) |
9(19) |
33(67) |
0 |
8(16) |
41(84) |
||
|
Cartilage invasion |
0.128 |
0.129* |
|||||||
|
No |
69 |
15(22) |
25(36) |
29(42) |
10(14) |
13(19) |
46(67) |
||
|
Yes |
71 |
11(16) |
18(25) |
42(59) |
0 |
15(21) |
56(79) |
||
|
|
|||||||||
|
*: Mild and negative cells were combined in VEGF line because of less than 5 in some cells (Fisher's exact test). MVD, microvessel density; PTEN, phosphatase and tensin homolog deleted in chromosome ten; VEGF, vascular endothelial growth factor. |
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|
Sullu et al. Diagnostic Pathology 2010 5:35 doi:10.1186/1746-1596-5-35 |
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