Table 1

Association of VEGF, PTEN expression and MVD with tumor grade in laryngeal carcinoma (mean ± standard error of mean).

PTEN

VEGF



N(%)

Negative

Mild

Severe

P

Negative

Mild

Severe

P

MVD*

P


Grade

0.400

0.015

0.003

Grade 1

76

11(14)

27(36)

38(50)

7(9)

18(24)

51(67)

43.0 ± 2.6

Grade 2

41

6(15)

11(27)

24(58)

2(5)

10(24)

29(71)

40.4 ± 2.8

Grade 3

23

9(39)

5(22)

9(39)

1(4)

22(96)

59.5 ± 5.8


Total (%)

140

26(18)

43(31)

71(51)

10(7)

28(20)

102(73)


*p: grade 1 vs 3 = 0.007; grade 2 vs 3 = 0.04; MVD, microvessel density; PTEN, phosphatase and tensin homolog deleted in chromosome ten; VEGF, vascular endothelial growth factor;

Sullu et al. Diagnostic Pathology 2010 5:35   doi:10.1186/1746-1596-5-35

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