Table 1 |
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|
Association of VEGF, PTEN expression and MVD with tumor grade in laryngeal carcinoma (mean ± standard error of mean). |
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|
PTEN |
VEGF |
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|
|
|
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|
N(%) |
Negative |
Mild |
Severe |
P |
Negative |
Mild |
Severe |
P |
MVD* |
P |
|
|
|
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|
Grade |
0.400 |
0.015 |
0.003 |
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|
Grade 1 |
76 |
11(14) |
27(36) |
38(50) |
7(9) |
18(24) |
51(67) |
43.0 ± 2.6 |
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|
Grade 2 |
41 |
6(15) |
11(27) |
24(58) |
2(5) |
10(24) |
29(71) |
40.4 ± 2.8 |
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|
Grade 3 |
23 |
9(39) |
5(22) |
9(39) |
1(4) |
22(96) |
59.5 ± 5.8 |
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|
|
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|
Total (%) |
140 |
26(18) |
43(31) |
71(51) |
10(7) |
28(20) |
102(73) |
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|
|
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|
*p: grade 1 vs 3 = 0.007; grade 2 vs 3 = 0.04; MVD, microvessel density; PTEN, phosphatase and tensin homolog deleted in chromosome ten; VEGF, vascular endothelial growth factor; |
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|
Sullu et al. Diagnostic Pathology 2010 5:35 doi:10.1186/1746-1596-5-35 |
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