Analysis of plasma cell count in bone marrow aspirate (BMA) and bone marrow biopsy (BMB). (a) Box and whisker plot (T-test) showing significant difference in plasma cell count between BMA and BMB analysis. Higher values were observed in pathologist (BMB) (mean 47.712 ± 24.8) and computer image analysis (CIA) (mean 44.113 ± 30.6) as compared with (BMA) cytologist report (mean 30.649 ± 17.1) (P < 0.001 and P < 0.0048, respectively). (b) Scatter plots showing correlation between CIA and BMB; BMA and BMB; CIA and BMA. Correlation of BMB assessment: pathologist and CIA counting (r = 0.8; P < 0.0001), pathologist and cytologist counting (r = 0.321; P = 0.015), and percentage of plasma cells in BMA and CIA (r = 0.27; P = 0.05).
Štifter et al. Diagnostic Pathology 2010 5:30 doi:10.1186/1746-1596-5-30