Table 2

Association between immunoreactivity for NE markers and histological subtype of RCC.

Immunoreactivity

Histological subtype

Marker

negative, n (%)

positive, n (%)

p-value

clear cell

serotonin

121 (93)

9 (7)

0.2

papillary

6 (75)

2 (25)

chromophobic

4 (80)

1 (20)

unclassified

2 (100)

0 (0)

clear cell

CD56

105 (82)

23 (18)

0.9

papillary

7 (78)

2 (22)

chromophobic

4 (80)

1 (20)

unclassified

2 (100)

0 (0)

clear cell

NSE

62 (48)

67 (52)

0.01

papillary

8 (80)

2 (20)

chromophobic

4 (100)

0 (0)

unclassified

2 (100)

0 (0)

clear cell

synaptophysin

130 (99)

1 (1)

0.2

papillary

9 (90)

1 (10)

chromophobic

5 (100)

0 (0)

unclassified

2 (100)

0 (0)

Ronkainen et al. Diagnostic Pathology 2010 5:28   doi:10.1186/1746-1596-5-28