Table 3

Localization and immunostaining intensity of VEGF expression in placental villous tissues

Normal pregnancy

(n: 55)

IUGR

(n: 55)

Statistical comparison

P value


Score

0

n (%)

1+

n (%)

2+

n (%)

3+

n (%)

0

n (%)

1+

n (%)

2+

n (%)

3+

n (%)

P*


CVSC

-

55 (100)

-

-

-

-

-

55 (100)

<0.001

VSMC

-

55 (100)

-

-

-

-

-

55 (100)

<0.001

VVEC

-

55 (100)

-

-

-

-

-

55 (100)

<0.001

ST

-

55 (100)

-

-

-

-

-

55 (100)

<0.001

CT

-

55 (100)

-

-

-

-

-

55 (100)

<0.001

EVT

55 (100)

-

-

-

-

-

55 (100)

<0.001


IUGR: Intrauterine growth restricted; CVSC: Chorionic villous stromal cells; VSMC: Vascular smooth muscle cells; VVEC: Villous vascular endothelial cells; ST: Syncytiotrophoblasts; CT; Cytotrophoblasts; EVT: Extravillous trophoblasts [Staining intensity of VEGF were scored as follows: 0 (negative), weak (1+), moderate (2+), and strong (3+)] *P: Statistical comparison of normal and IUGR placental tissues

Barut et al. Diagnostic Pathology 2010 5:24   doi:10.1186/1746-1596-5-24

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