A: Liver with multiple nodules in the left lobe, largest (5 × 6 cm) with thrombus in the left main branch of the portal vein (arrow). B: Neoplastic cells with prominent nucleoli, abundant cytoplasm and some with hyaline globules within it (arrow) (H&E × 400). C: Portal triad with dense lymphocytic infiltrate. Note the absence of bile ducts. (H&E × 40). D: Dense lymphocytic infiltrate present beside damaged bile duct with surrounding epithelioid granulomatous reaction (H&E × 100). E: Larger interlobular bile ducts with hyperplastic changes in the lining epithelium (H&E × 40).
Gupta et al. Diagnostic Pathology 2009 4:45 doi:10.1186/1746-1596-4-45