A case of non-invasive serous adenocarcinoma at unilateral fimbria with spread to the peritoneal/uterine cavity: case report
1 Department of Human Pathology, Juntendo University, Tokyo, Japan
2 Department of Tumor and Pathology, Juntendo University, Tokyo, Japan
3 Department of General Medicine, Juntendo University, Tokyo, Japan
4 Department of Gynecology and Obstetrics, Juntendo University, Tokyo, Japan
Diagnostic Pathology 2009, 4:43 doi:10.1186/1746-1596-4-43Published: 5 December 2009
Recently, fimbriae have been identified as a possible arising site for the pelvic serous carcinoma (PSC) both in BRCA-positive and BRCA-negative women. Although non-invasive (intraepithelial) serous adenocarcinoma of the fimbria has been found in specimens obtained from prophylactic salphingo-oophorectomies in BRCA-positive women, there has not been any case report in clinical situation, since this type of tumor is usually detected after stromal invasion/widespread dissemination. We describe a 67-year-old woman with non-invasive serous adenocarcinoma located solely in the left fimbria. This case may suggest the benefit of endometrial cytology and detailed gross examination of fimbria for the early detection of fimbrial carcinoma. This case may provide evidence suggesting fimbrial intraepithelial adenocarcinoma is one cause of PSC.