Table 1

Chronic changes noted in renal allograft biopsies of 2 groups, Ahmedabad Tolerance Induction Protocol (ATIP) vs. controls:

Biopsies

ATIP

Controls


(n = 1151)

(n = 974)

(n = 177)



Chronic changes (n = 135)

107 (10.98%)

31 (17.5%)


Mean follow-up (months) (range)

130.9 (23–277)

151.9 (13.9–280)


Male: female

87:20:00

21:10


Hypertension (BP > 130/90 mm Hg)

71 (66.4%)

13 (41.9%)


Proteinuria (24 hrs urine albumin > 800 mg)

46 (43%)

25(80.6%)


HISTOPATHOLOGY


Interstitial fibrosis+ tubular atrophy

107 (100%)

31 (100%)


Focal global sclerosis

50 (46.7%)

21 (67.7%)


Chronic transplant glomerulopathy

35 (32.7%)

15 (48.4%)


C4d deposits

2(1.9%)

6 (19.4%)


Acute on chronic calcineurin inhibitor toxicity

77 (71.9%)

15 (48.4%)


Acute on chronic T/B cell rejection

30 (28.1%)

16 (51.6%)


Patel et al. Diagnostic Pathology 2009 4:4   doi:10.1186/1746-1596-4-4

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