Table 1

The B-Classification and the histologic expression

Classification

Definition


B1

normal

Normal or not interpretable tissue

- benign parenchyma with or without minimal changes

- artifacts, bleeding

B2

Benign

Benign Lesion

- fibrocystic changes

- fibro adenoma

- sclerosing adenosis

-ectasia, abscess, fat tissue necrosis

- small intraductal papilloma

B3

benign, but with increased risk of malignancy or an association with a malignant tumor

Lesion with uncertain malignant potential

- large or multiple papillary lesions with or without atypia

- scar, complex sclerosing lesion

- lobular intraepithelial neoplasia (LIN)

- ADH

- phylloid tumor or unclear fibroepithelial tumor

B4

suspect

Suspect for malignancy

B5

malignant

Malignant Lesions

a) ductal Carcinoma in situ (DCIS)

LIN (CLIS) of pleomorphic subtype G3

LIN with comedo necrosis

b) Carcinoma

c) status of invasion not decidable

d) other malignant tumor such as Lymphoma, metastasis or sarcoma


Wienert et al. Diagnostic Pathology 2009 4:3   doi:10.1186/1746-1596-4-3

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