Table 2

Relationship between core biopsy features and margin status (univariate analysis)**

Overall (n = 40)

Breast conserving surgery specimens (n = 22), margin status

Mastectomy specimens (n = 18), margin status

Core biopsy features

≤ 0.2 cm

(n = 21)

> 0.2 cm

(n = 19)

p

≤ 0.2 cm

(n = 13)

> 0.2 cm

(n = 9)

p

≤ 0.2 cm

(n = 8)

> 0.2 cm

(n = 10)

p


Maximum nuclear grade 3/3

(n = 18)

9

9

1

3

3

1

6

6

1

Maximum nuclear grade 2/3

(n = 22)

12

10

0.76

10

6

0.29

2

4

0.57

Necrosis present

(n = 33)

16

17

1

10

8

0.74

6

9

0.47

Comedo-pattern present

(n = 16)

8

8

1

3

2

NA

5

6

1

Cancerization of lobules present

(n = 21)

9

12

0.54

4

5

1

5

7

0.68

Number of tissue cores processed (mean)

8.6

9.4

0.56

9.4

8.4

0.66

7.25

10.3

0.08

DCIS ducts per tissue core (mean)

5.9

6.1

0.85

6

4.2

0.17

5.9

7.9

0.35

Number of tissue cores with DCIS

4.42

5.05

0.45

4.23

3.89

0.68

4.75

6.1

0.31

Total DCIS ducts (mean)

25.9

31.4

0.49

23.1

17.6

0.35

30.25

43.9

0.4

Solid Pattern present

(n = 37)

20

17

0.64

13

7

0.11

7

10

0.49

Micropapillary pattern present

(n = 10)

6

4

0.66

3

2

NA

3

2

NA

Cribriform pattern present

(n = 18)

8

10

0.53

5

5

1

3

5

0.62

Clinging pattern present

(n = 4)

3

1

NA

0

1

NA

3

0

NA


DCIS ductal carcinoma in-situ; **excludes cases in which no residual DCIS was found in the excision; NA not applicable

Fadare et al. Diagnostic Pathology 2009 4:26   doi:10.1186/1746-1596-4-26

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