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Open Access Highly Accessed Case Report

A unique case of urinary bladder simple melanosis: a case report and review of the literature

Bo Jin1*, Syed Y Zaidi1, Melvin Hollowell2, Christopher Hollowell2 and Husain Saleh1

Author affiliations

1 Department of Pathology, Sinai-Grace Hospital/Detroit Medical Center, Wayne State University School of Medicine, 6071 West Outer Drive, Detroit, MI 48235 USA

2 Department of Urology, Sinai-Grace Hospital/Detroit Medical Center, Wayne State University School of Medicine, 6071 West Outer Drive, Detroit, MI 48235 USA

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Citation and License

Diagnostic Pathology 2009, 4:24  doi:10.1186/1746-1596-4-24

Published: 22 July 2009

Abstract

Melanosis refers to abnormal or excessive deposition of melanin pigment in the cells and/or tissue, which can be seen in any organ but commonly in skin and oral mucosa. Melanosis of the urinary bladder is an extremely rare benign condition and only a handful of cases been reported in the English literature before. In this article, we report a new case of urinary melanosis, describe the differential diagnostic features from pseudomelanosis and offer clues for correct diagnosis. We also provide comprehensive review of the literature on the subject.