Table 1 |
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Immunohistochemical analysis of p16INK4A expression in tissue microarray cores from 806 cervix biopsies containing normal tissues, CIN1, CIN2, CIN3, and invasive cervical carcinoma (ICC), evaluated using the simple protocol. |
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p16INK4A immunostaining |
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|
|
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n |
Negative* |
Positive# |
|
|
|
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|
Normal cervix |
10 |
10 (100.0) |
0 (0) |
|
CIN1 |
249 |
69 (27.7) |
180 (72.3) |
|
CIN2 |
233 |
21 (9.0) |
212 (91.0) |
|
CIN3 |
181 |
3 (1.7) |
178 (98.3) |
|
ICC |
133 |
2 (1.5) |
131 (98.5) |
|
|
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*Negative: no staining or weak staining in less than 10% of epithelial cells. #Positive: moderate or strong staining in more than 10% of epithelial cells. |
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Lesnikova et al. Diagnostic Pathology 2009 4:22 doi:10.1186/1746-1596-4-22 |
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