Table 1

Detailed Description of Discordant Cases (N = 28)

S. No.

Diagnosis

Hale's stain

Vimentin

CK 7

Vinculin

EM

Final Diagnosis

1

CCRCC vs papillary

-

-

-

Papillary RCC

2

CCRCC vs Chromophobe

-

+

-

-

Conventional RCC

3

Papillary RCC vs CCRCC

-

-

-

Conventional RCC

4

Chromophobe RCC vs CCRCC

+

+

3+, m

-

PNV

Chromophobe RCC

5

Papillary RCC vs CCRCC

3+

+

-

Papillary RCC

6

Collecting duct RCC vs Papillary

2+

3+

-

Papillary RCC

7

CCRCC vs papillary

+

2+

-

Papillary RCC

8

ACC vs CCRCC

3+

-

-

Conventional RCC

9

Chromophobe RCC vs CRCC

+

-

2+, m

-

Chromophobe RCC

10

CCRCC vs Papillary

+

-

-

Conventional RCC

11

Collecting duct RCC vs CCRCC

2+

2+

2+

Collecting duct RCC

12

CCRCC vs oncocytoma

-

-

-

Conventional RCC

13

Chromophobe vs CCRCC

-

+

-

-

Conventional RCC

14

Chromophobe vs CCRCC

+

-

2+, m

-

PNV

Chromophobe RCC

15

Chromophobe vs CCRCC

-

-

-

-

Conventional RCC

16

CCRCC vs papillary

-

+

-

Papillary RCC

17

CCRCC vs Sarcomatoid

-

-

-

Sarcomatoid RCC

18

Papillary RCC vs CCRCC

+

2+

-

Papillary RCC

19

Chromophobe vs CCRCC

+

-

2+, m

-

Chromophobe RCC

20

Chromophobe RCC vs CCRCC

-

-

-

-

Glycogen

Conventional RCC

21

Chromophobe vs CCRCC

-

2+

-

-

Conventional RCC

22

CCRCC vs chromophobe

-

3+

3+

-

Papillary RCC

23

Chromophobe vs oncocytoma

-

3+

-

PNV

Chromophobe RCC

24

CC RCC vs papillary

2+

3+

-

No PNV

Papillary RCC

25

Chromophobe vs CCRCC

+

2+

+

-

Chromophobe RCC

26

CCRCC vs Chromophobe

+

-

3+, m

-

Chromophobe RCC

27

CCRCC vs papillary

-

-

-

Conventional RCC

28

Oncocytoma vs ACC vs CCRCC

-

-

-

Conventional RCC

CCRCC – Conventinal/clear cell RCC, ACC – adrenocortical carcinoma, m – membranous accentuation, PNV-Perinuclear vesicles

Pradhan et al. Diagnostic Pathology 2009 4:21   doi:10.1186/1746-1596-4-21