Table 1

Sensitivity, specificity, and positive (PPV) and negative predictive value (NPV) for cytology, ImmunoCyt/uCyt+, CK20 and combinations.

BiOPSY

RESULT

TEST

RESULT


LGUC

n = 31

HGUC

n = 23

Negative

Sensitivity

Specificity

PPV

NPV

OA


Cytology

+

21

20

12

75.9

66.7

77.3

88.9

72.2

-

10

3

24

UCyt+™

+

24

21

5

83.3

86.1

90.0

79.5

84.4

-

7

2

31

CK20

+

20

18

6

70.4

83.3

86.3

65.2

75.5

-

11

5

30

Cytology+ UCyt+™

+

26

22

5

88.9

86.1

90.5

86.1

87.7

-

5

1

31

Cytology+ CK20

+

22

20

12

77.8

66.7

77.7

66.7

73.3

-

9

3

24

UCyt+™+ CK20

+

23

21

7

81.5

80.5

86.3

74.3

81.1

-

8

2

29

Cytology+ UCyt+™ + CK20

+

28

22

12

92.5

66.7

80.6

85.7

82.2

-

3

1

24


+: Positive test result, -: Negative test result Negative: Negative for malignancy PPV:Positive predictive value NPV: Negative predictive value OA: Overall accuracy

Soyuer et al. Diagnostic Pathology 2009 4:20   doi:10.1186/1746-1596-4-20

Open Data