Table 1 |
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|
Sensitivity, specificity, and positive (PPV) and negative predictive value (NPV) for cytology, ImmunoCyt/uCyt+, CK20 and combinations. |
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|
BiOPSY |
RESULT |
TEST |
RESULT |
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|
|
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|
LGUC n = 31 |
HGUC n = 23 |
Negative |
Sensitivity |
Specificity |
PPV |
NPV |
OA |
||
|
|
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|
Cytology |
+ |
21 |
20 |
12 |
75.9 |
66.7 |
77.3 |
88.9 |
72.2 |
|
- |
10 |
3 |
24 |
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|
UCyt+™ |
+ |
24 |
21 |
5 |
83.3 |
86.1 |
90.0 |
79.5 |
84.4 |
|
- |
7 |
2 |
31 |
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|
CK20 |
+ |
20 |
18 |
6 |
70.4 |
83.3 |
86.3 |
65.2 |
75.5 |
|
- |
11 |
5 |
30 |
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|
Cytology+ UCyt+™ |
+ |
26 |
22 |
5 |
88.9 |
86.1 |
90.5 |
86.1 |
87.7 |
|
- |
5 |
1 |
31 |
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|
Cytology+ CK20 |
+ |
22 |
20 |
12 |
77.8 |
66.7 |
77.7 |
66.7 |
73.3 |
|
- |
9 |
3 |
24 |
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|
UCyt+™+ CK20 |
+ |
23 |
21 |
7 |
81.5 |
80.5 |
86.3 |
74.3 |
81.1 |
|
- |
8 |
2 |
29 |
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|
Cytology+ UCyt+™ + CK20 |
+ |
28 |
22 |
12 |
92.5 |
66.7 |
80.6 |
85.7 |
82.2 |
|
- |
3 |
1 |
24 |
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|
|
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|
+: Positive test result, -: Negative test result Negative: Negative for malignancy PPV:Positive predictive value NPV: Negative predictive value OA: Overall accuracy |
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|
Soyuer et al. Diagnostic Pathology 2009 4:20 doi:10.1186/1746-1596-4-20 |
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