Table 2

Reported cytogenetic translocations involving Xp11.2/transcription factor E3 (TFE3)

Chromosome Translocation

Gene Fusion

Neoplasm

Source, Year

der(17)t(X;17)(p11.2;q25)

ASPL-TFE3

ASPS

Argani et al, 2001 [1];

Argani et al, 2007 [17]

t(X;17)(p11.2;q25)

ASPL-TFE3

RCC

Argani et al, 2001 [1];

Argani et al, 2007 [17]

t(X;1)(p11.2;q21)

PRCC-TFE3

RCC

Argani et al, 2007 [17]

t(X;1)(p11.2;p34)

PSF-TFE3

RCC

Argani et al, 2007 [17]

inv(X)(p11.2;q12)

NONO-TFE3

RCC

Argani et al, 2007 [17]

t(X;17)(p11.2;q23)

CLTC-TFE3

RCC

Argani et al, 2003 [8];

Argani et al, 2007 [17]

t(X;3)(p11.2;q23)

Unknown

RCC

Argani et al, 2007 [17]

ASPL, alveolar soft part sarcoma locus; ASPS, alveolar soft part sarcoma; CLTC, clathrin heavy chain; NONO, non-POU domain-containing octamer-binding; PRCC, papillary renal cell carcinoma; PSF, polypyrimidine tract binding protein-associated splicing factor; RCC, renal cell carcinoma

Armah et al. Diagnostic Pathology 2009 4:15   doi:10.1186/1746-1596-4-15