Table 1

Immunohistochemical findings of case of Xp11.2 translocation renal cell carcinoma with a novel translocation involving chromosome 19

Antibody to

Result (Positive, Negative)

Intensity (Strong, Moderate, Weak)

Immunoreactivity (1+, 2+, 3+)

Staining Pattern (Nuclear, Cytoplasmic)

TFE3

Positive

Strong

3+

Nuclear

Cytokeratin AE1-AE3

Positive

Moderate

2+

Cytoplasmic

Cytokeratin CAM-5.2

Positive

Moderate

2+

Cytoplasmic

Cytokeratin 7

Positive

Weak

1+

Cytoplasmic

Epithelial membrane antigen

Positive

Strong

3+

Cytoplasmic

Renal cell carcinoma antigen

Positive

Weak

1+

Cytoplasmic

CD 10

Positive

Strong

3+

Cytoplasmic

E-cadherin

Positive

Strong

3+

Cytoplasmic

Calveolin

Positive

Moderate

2+

Cytoplasmic

Parvalbumin

Positive

Moderate

2+

Cytoplasmic

Colloidal iron

Positive

Weak

1+

Cytoplasmic

BerEP4

Negative

Not Applicable

Not Applicable

Not Applicable

Carbonic anhydrase IX

Negative

Not Applicable

Not Applicable

Not Applicable

1+, < 25% Positive Cells; 2+, 25–50% Positive Cells; 3+, > 50% Positive Cells

Armah et al. Diagnostic Pathology 2009 4:15   doi:10.1186/1746-1596-4-15