Table 1

Immunohistochemical findings of case of Xp11.2 translocation renal cell carcinoma with a novel translocation involving chromosome 19

Antibody to

Result (Positive, Negative)

Intensity (Strong, Moderate, Weak)

Immunoreactivity (1+, 2+, 3+)

Staining Pattern (Nuclear, Cytoplasmic)


TFE3

Positive

Strong

3+

Nuclear


Cytokeratin AE1-AE3

Positive

Moderate

2+

Cytoplasmic


Cytokeratin CAM-5.2

Positive

Moderate

2+

Cytoplasmic


Cytokeratin 7

Positive

Weak

1+

Cytoplasmic


Epithelial membrane antigen

Positive

Strong

3+

Cytoplasmic


Renal cell carcinoma antigen

Positive

Weak

1+

Cytoplasmic


CD 10

Positive

Strong

3+

Cytoplasmic


E-cadherin

Positive

Strong

3+

Cytoplasmic


Calveolin

Positive

Moderate

2+

Cytoplasmic


Parvalbumin

Positive

Moderate

2+

Cytoplasmic


Colloidal iron

Positive

Weak

1+

Cytoplasmic


BerEP4

Negative

Not Applicable

Not Applicable

Not Applicable


Carbonic anhydrase IX

Negative

Not Applicable

Not Applicable

Not Applicable


1+, < 25% Positive Cells; 2+, 25–50% Positive Cells; 3+, > 50% Positive Cells

Armah et al. Diagnostic Pathology 2009 4:15   doi:10.1186/1746-1596-4-15

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